Tailor-made consulting by Bosch

- advanced laboratories for development and scale-up

  • October 15, 2012
  • Tailor-made consulting by Bosch
    Tailor-made consulting by Bosch

Bosch Packaging Technology offers pharmaceutical manufacturers a tailormade consulting service for all laboratory requirements. The company operates a number of laboratories equipped with the latest systems and machinery for pharmaceutical solids. Customers can rent the labs for research purposes and on-site testing. Bosch quickly and reliably supports customers worldwide with its concept for formulation and pharmaceutical process development.

As a part of Bosch Packaging Technology, Hüttlin GmbH, based in Schopfheim, Germany, is backed by many years of experience. The strategic focus for the consulting service is on the continuous development of specialized centers in Germany and throughout the world. These centers of excellence offer customers the essentials for advanced product development in the form of a series of experiments and stand-alone tests. Supplemented by specific training sessions for employees, these centers combine theoretical and practical aspects.

The Hüttlin Service Center in Schopfheim offers more than 300 square meters of space with state-of-the-art equipment for developing and producing solid materials. The machines cover all process steps: from mixing and granulating, drying and coating through to pressing and coating of tablets and pellets, as well as capsule filling. The laboratory includes eleven systems for batch sizes ranging from 30 grams to 300 kilograms. This is why Hüttlin offers ideal conditions for test series of new products, formula development or optimization of individual aspects.

“With our full range of analytical equipment, we consistently generate the latest results to verify the development process,” explained Dr. Marcus Knöll, Head of Pharma Service at Hüttlin. “In a further step, this data enables an easy scale-up.” Using this approach, individual parameters can be adapted to the needs of the production situation at the customer site. Bosch experts are on hand to support optimal development work and fastest possible results.

The Service Center is not only suitable for development work, it also promotes the transfer of interdisciplinary expertise. In tailor-made training courses and seminars, participants receive specific training focusing on machinery, equipment and processes. This takes place at one of the Bosch training centers or directly on-site. These training sessions cover a variety of topics including maintenance, validation, qualification, cleaning, safety, experimental design, productivity and scale-ups.

The seminar series “Expert of Solids” and “Master of Solids” offer participants specific knowledge in the production and processing of solid pharmaceuticals. In the theoretical and practical training sessions, selected lecturers impart basic skills related to processes ranging from granulation and coating to tablet pressing. The seminars can be completed on an extraoccupational basis, and certification is awarded to successful participants.

In addition to the Hüttlin Service Center in Schopfheim, Bosch operates several other laboratories and training centers. While test series for tablet coating are conducted in Knowsley, UK, the focus in Waiblingen, Germany is on micro-dosing and capsule filling. Currently, additional laboratories for basic research are being implemented in key markets. These research centers offer ultra-modern equipment for high quality and efficient testing.